筑波大学

ジャーナルクラブ -Journal Club-

ジャーナルクラブ

Date Presented by Article
2022.9.22 Hirofumi Toko Single cell sequencing identifies clonally expanded synovial CD4 + T PH cells expressing GPR56 in rheumatoid arthritis.
Alexandra Argyriou,et al.
Nat Commun.13(1):4046,2022
2022.9.15 Tamaki Iwai Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis.
Yuye Yin,et al.
Nat Immunol.23(9):1342-1354,2022
2022.9.8 Hiromitsu Asashima Granzyme K + CD8 T cells form a core population in inflamed human tissue.
A Helena Jonsson,et al.
Sci Transl Med. 14(649),2022
2022.7.28 Ryota Sato Tfh cells with NLRP3 inflammasome activation are essential for high-affinity antibody generation, germinal centre formation and autoimmunity.
Zhenhuan Zhao,et al.
Ann Rheum Dis. 81(7):1006-1012,2022
2022.7.21 Ayako Ohyama Single-cell transcriptomic analysis identifies an immune-prone population in erythroid precursors during human ontogenesis.
Changlu Xu,et al.
Nat Immunol. 23(7):1109-1120,2022
2022.7.14 Reona Tanimura Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking.
Timothy A Gottschalk, et al.
Front Immunol.13:875359,2022
2022.7.7 Haruka Miki Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.
Ilya Korsunsky, et al.
Med. 3(7):481-518,2022
2022.6.30 Ayako Kitada Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.
Sabrina Meisgen et al.
Ann Rheum Dis. 221714,2022
2022.6.9 Taihei Nishiyama Cytoplasmic DNA sensing by KU complex in aged CD4 + T cell potentiates T cell activation and aging-related autoimmune inflammation.
Yan Wang, et al.
Immunity.54(4):632-647,2021
2022.6.2 Hirofumi Toko KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
Jing Li, et al.
Science.376(6590),2022
2022.5.26 Tamaki Iwai Natural Killer Cells Infiltration in the Joints Exacerbates Collagen-Induced Arthritis.
Lisheng Wu, et al.
Front Immunol. 13:860761,2022
2022.5.12 Reona Tanimura TLR7 gain-of-function genetic variation causes human lupus.
Grant J Brown, et al.
Nature. 605(7909):349-356,2022
2022.3.10 Tamaki Iwai PD-1 agonism by anti-CD80 inhibits T cell activation and alleviates autoimmunity.
Daisuke Sugiura, et al.

Nat Immunol. 23(3):399-410,2022
2022.3.3
Taihei Nishiyama Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice.
Cecilia B Cavazzoni, et al.
Cell Rep. 38(8):110399,2022
2022.2.17 Hirofumi Toko The CD6/ALCAM pathway promotes lupus nephritis via T cell-mediated responses.
Samantha A Chalmers, et al.
J Clin Invest. 132(1):e147334,2022
2022.2.10 Fumika Honda Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation.
Bowen Wu, et al.
Nat Immunol. 22(12):1551-1562,2021
2022.2.3 Yuya Kondo Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers.
Wenzhi Song, et al.
Immunity. 55(2):290-30,2022